The rise and fall of Hox gene clusters

The rise and fall of Hox gene clusters

Denis Duboule

Development 134, 2549-2560(2007) doi:10.1242/dev.001065

The role of Hox genes during vertebrate limb development

The role of Hox genes during vertebrate limb development.

Zakany J, Duboule D.

Curr Opin Genet Dev. 2007 Aug;17(4):359-66 doi:10.1016/j.gde.2007.05.011

Part of: Volume 17, Issue 4, Pages 259-368 (August 2007) Pattern formation and developmental mechanisms
Edited by Ross Cagan and Christine Hartmann

Hox Genes and Axial Specification in Vertebrates

Hox Genes and Axial Specification in Vertebrates

Ann Campbell Burke and Julie L. Nowicki

American Zoologist 2001 41(3):687-697; doi:10.1093/icb/41.3.687

INTRODUCTION
Experimental embryology provides a means for exploring the intrinsic mechanisms that underlie morphological evolution. This paper will discuss experimental results that explore the evolutionary significance of Hox gene expression in the patterning of the anterior-posterior (AP) axis in vertebrates. The detailed experiments are reported elsewhere (Nowicki and Burke, 2000). This paper will focus on a discussion of their relevance to understanding the role developmental mechanisms play in generating axial pattern, and how those mechanisms may act as nodal points in the evolution of morphology.

Hox genes and morphological identity: axial versus lateral patterning in the vertebrate mesoderm

Hox genes and morphological identity: axial versus lateral patterning in the vertebrate mesoderm [direct to reprint link]

JL Nowicki and AC Burke

Development, Vol 127, Issue 19 4265-4275