Articles tagués Chick

An anteroposterior wave of vascular inhibitor downregulation signals aortae fusion along the embryonic midline axis

An anteroposterior wave of vascular inhibitor downregulation signals aortae fusion along the embryonic midline axis

Robert J. Garriock, Catherine Czeisler, Yasuo Ishii, Alicia M. Navetta and Takashi Mikawa

Development 137, 3697-3706, doi: 10.1242/dev.051664

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part of fig 1 of the paper

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Tuning the mechanosensitivity of a BK channel by changing the linker length

Tuning the mechanosensitivity of a BK channel by changing the linker length

Hucheng Zhao, Masahiro Sokabe

Cell Research (2008 ): 1-8

Il semble fréquent pour les personnes travaillant sur la mécano-sensibilité biologique d’oublier ce qui la détermine en premier lieu, à savoir les composants cellulaires codés par le génome. Suite à une discussion in-RL, liée au travail d’E. Farge que Tom Roud nous présentait il y a quelques jours, j’ai sorti un vieux papier de K Yoshimura, T Nomura and M Sokabe Loss-of-function mutations at the rim of the funnel of mechanosensitive channel MscL. Biophys J (2004) vol. 86 (4) pp. 2113-20, où les auteurs caractérisent des mutations résultant à une perte de fonction. Ils montrent ainsi le déterminisme génétique de la MS, mais c’est une situation « on-off » et on est chez les bactéries, ce qui n’était pas tout à fait du goût de mes interlocuteurs, qui auraient préféré un travail sur des cellules eucaryotes et plutôt une modulation de l’activité MS à la place de la perte de fonction.

En cherchant la biblio du Dr Masahiro Sokabe j’ai trouvé mon bonheur, juste pour être frustré parce que le papier était inaccessible par mon canal bibliographique. Une demande de tiré-à-part plus tard j’ai pu lire son dernier papier publié dans Cell Research, dont la référence est donnée en châpeau et l’abstract en bas de post.

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Multicellular rosette formation during cell ingression in the avian primitive streak

Multicellular rosette formation during cell ingression in the avian primitive streak

Laura J. Wagstaff, Gemma Bellett, Mette M. Mogensen, Andrea Münsterberg

Developmental Dynamics Volume 237, Issue 1, Pages 91-96

Where one can see differences in cytoskeletal organization (and cells’ organization as well) at the primitive streak of gastrulating chick embryos. Differences that some model failed to take in account ; oh dear, how fucking annoying, for the model…

Below the fold, my favorite, panel C of Figure 3 of the paper (and abstract):

C: Side view of a HH3 primitive streak anterior region, with microtubule staining in green and actin staining in red. Actin-rich parts are protruding towards the hypoblast. Scale bars = 20 mm.

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Darwin Was Wrong, New Research Shows

Sans blagues !

Le mec c’est planté, quant à l’origine du poulet (j’en connais un qui doit jubiler en lisant, un spécialiste du poulet)

Charles Darwin maintained that the domesticated chicken descended from the red junglefowl, but new research from Uppsala University now shows that the wild origins of the chicken are more complicated than that.

Yellow-skinned chickens have a different version of a gene than their white-skinned cousins. Darwin believed that all chickens came from a wild species known as the red junglefowl. When the researchers looked for the yellow-skin gene in the red junglefowl, they only found the genetic variant that codes for white skin. More surprisingly, when they finally did find the yellow-skin version of the gene, it was present in a completely different wild species: the grey junglefowl.

Or how to make a title sexy. OK, let’s make this blogpost sexy (a little bit), with a yellow (almost) sexy, probably domestic, chick.

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Elle enlève le haut et le ‘tit bout de bas et elle n’est plus jaune à mon avis…

Ah ! merde alors, c’est tout ? En plus un gène qui déterminerait quelque chose ? Enfin, ce n’est que de la couleur, respirons.

Identification of the Yellow Skin Gene Reveals a Hybrid Origin of the Domestic Chicken

Jonas Eriksson, Greger Larson, Ulrika Gunnarsson, Bertrand Bed’hom, Michele Tixier-Boichard, Lina Strömstedt, Dominic Wright, Annemieke Jungerius, Addie Vereijken, Ettore Randi, Per Jensen, Leif Andersson

Yellow skin is an abundant phenotype among domestic chickens and is caused by a recessive allele (W*Y) that allows deposition of yellow carotenoids in the skin. Here we show that yellow skin is caused by one or more cis-acting and tissue-specific regulatory mutation(s) that inhibit expression of BCDO2 (beta-carotene dioxygenase 2) in skin. Our data imply that carotenoids are taken up from the circulation in both genotypes but are degraded by BCDO2 in skin from animals carrying the white skin allele (W*W). Surprisingly, our results demonstrate that yellow skin does not originate from the red junglefowl (Gallus gallus), the presumed sole wild ancestor of the domestic chicken, but most likely from the closely related grey junglefowl (Gallus sonneratii). This is the first conclusive evidence for a hybrid origin of the domestic chicken, and it has important implications for our views of the domestication process.


via Sciencedaily Et si je me payais un KFC ce soir ? Pour fêter ça 🙂

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Cessation of gastrulation is mediated by suppression of EMT at the VER

Cessation of gastrulation is mediated by suppression of epithelial-mesenchymal transition at the ventral ectodermal ridge

Sho Ohta, Kentaro Suzuki, Katsuro Tachibana, Hideaki Tanaka and Gen Yamada

Development 134, 4315-4324(2007) doi:10.1242/dev.008151

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