Young, J. J., Grayson, P., & Tabin, C. J. (2019). Developmental Biology: Hox Timing Determines Limb Placement. Current Biology, 29(2), R52–R54.
Hox genes are known to determine vertebral identity along with being required for normal limb patterning. A new study now finds that differential expression timing of Hox genes in the lateral plate mesoderm determines limb placement as well.