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Archive de la catégorie «differentiation»

Mouse Study Can Illuminate How Tumors Manipulate The Human Vascular System: — Tumors use the body’s blood system for their own purposes: They stimulate the growth of blood vessels that supply the tumor. Medical treatment blocks this process in order to restrain tumors. Scientists have now developed a method for producing a complex human vascular [...]

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HHMI News: Identifying the Genes that Put the “Stem” in Cell: “A team led by Howard Hughes Medical Institute (HHMI) researchers has identified a network of hundreds of genes that keep embryonic stem cells in their characteristic malleable state, able to develop into any cell type when the time comes. The finding, based on studies [...]

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Lhx2 Selector Activity Specifies Cortical Identity and Suppresses Hippocampal Organizer Fate
Vishakha S. Mangale, Karla E. Hirokawa, Prasad R. V. Satyaki, Nandini Gokulchandran, Satyadeep Chikbire, Lakshmi Subramanian, Ashwin S. Shetty, Ben Martynoga, Jolly Paul, Mark V. Mai, Yuqing Li, Lisa A. Flanagan, Shubha Tole, Edwin S. Monuki
Science 18 January 2008 Vol. 319. no. 5861, pp. 304 [...]

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Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism
Eric Dessaud, Lin Lin Yang, Katy Hill, Barny Cox, Fausto Ulloa, Ana Ribeiro, Anita Mynett, Bennett G. Novitch & James Briscoe
Nature 450, 717-720 (29 November 2007) | doi:10.1038/nature06347

Morphogens act in developing tissues to control the spatial arrangement of cellular differentiation. The activity of a [...]

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Inner ear hair cells produced in vitro by a mesenchymal-to-epithelial transition
Zhengqing Hu and Jeffrey T. Corwin
PNAS October 16, 2007 vol. 104 no. 42 www.pnas.orgcgidoi10.1073pnas.0704576104 (abstract below the fold).
And to make a bundle, a press release from ESF on New Stem Cells by Reprogramming. And just for the pleasure to read it once [...]

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