and the answer is: 101010

In binary!

10.10.10 10:10:10

Detection of Hypoxic Cells by Monoclonal Antibody Recognizing 2-Nitroimidazole Adducts

Detection of Hypoxic Cells by Monoclonal Antibody Recognizing 2-Nitroimidazole Adducts

Edith M. Lord, Lee Harwell, and Cameron J. Koch

CANCER RESEARCH 53, 5721-5726, December1, 1993

Role of myocardial hypoxia in the remodeling of the embryonic avian cardiac outflow tract

Role of myocardial hypoxia in the remodeling of the embryonic avian cardiac outflow tract

Yasuyuki Sugishita, Michiko Watanabe, and Steven A. Fisher

Developmental Biology 267 (2004) 294–308 doi:10.1016/j.ydbio.2003.11.017

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Two years ago, I pointed to a methodological flaw in one of the papers of Vincent Fleury, which didn’t contain data (or any consideration of) concerning the eventual contribution of hypoxia in one of the experimental settings. That was felt as a lèse majesté crime. The response was rather arrogant and this paper is a nice illustration of what I meant (and mean) about the eventual role of hypoxia. In the work of Sugishita et al. the hypoxic region is embedded in tissue otherwise normoxic. The red label (Cy3) pointed by the arrowheads indicate adducts by EF5, produced preferentially under hypoxic conditions.

So much for Fleury’s comment
This is the case for a normally developing embryo without any artificial occlusion impairing blood’s flow and oxygenation. Just imagine what kind of staining must result from impairing the blood flow!

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Now, what are the references for EF5 and the anti-EF5 monoclonals?

Webcam Piano 2.0

Vu sur Knowtex, posté par Mikaly

Historians Admit …

Historians Admit To Inventing Ancient Greeks

WASHINGTON—A group of leading historians held a press conference Monday at the National Geographic Society to announce they had “entirely fabricated” ancient Greece, a culture long thought to be the intellectual basis of Western civilization. [Read more]

Truth always come in the front stage.

The Twist Of Single Ladies

Jane Goodall

Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity

Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity

Tiina M. Asikainen, Ling-Yi Chang, Jacqueline J. Coalson, Barbara K. Schneider, Nahid S. Waleh, Machiko Ikegami, John M. Shannon, Vicki T. Winter, Peter Grubb, Ronald I. Clyman, Bradley A. Yoder, James D. Crapo, and Carl W. White

The FASEB Journal. 2006;20:1698-1700 doi: 10.1096/fj.06-5887fje

“No pressure, your choice”, my ass

There is a series of short ads to support 10:10. Maybe you have see it already, if not go on before reading the rest of my post.