The Angio-Fibrotic Switch of VEGF and CTGF in Proliferative Diabetic Retinopathy

Kuiper EJ, Van Nieuwenhoven FA, de Smet MD, van Meurs JC, Tanck MW, et al. (2008 ) The Angio-Fibrotic Switch of VEGF and CTGF in Proliferative Diabetic Retinopathy. PLoS ONE 3(7): e2675. doi:10.1371/journal.pone.0002675

Background
In proliferative diabetic retinopathy (PDR), vascular endothelial growth factor (VEGF) and connective tissue growth factor (CTGF) cause blindness by neovascularization and subsequent fibrosis, [...]

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Targeted Development of Registries of Biological Parts

Peccoud J, Blauvelt MF, Cai Y, Cooper KL, Crasta O, et al. (2008 ) Targeted Development of Registries of Biological Parts. PLoS ONE 3(7): e2671. doi:10.1371/journal.pone.0002671

Background
The design and construction of novel biological systems by combining basic building blocks represents a dominant paradigm in synthetic biology. Creating and maintaining a database of these building blocks is [...]

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Histone Deacetylases Control Neurogenesis in Embryonic Brain by Inhibition of BMP2/4 Signaling

Shakèd M, Weissmüller K, Svoboda H, Hortschansky P, Nishino N, et al. (2008 ) Histone Deacetylases Control Neurogenesis in Embryonic Brain by Inhibition of BMP2/4 Signaling. PLoS ONE 3(7): e2668. doi:10.1371/journal.pone.0002668

Background
Histone-modifying enzymes are essential for a wide variety of cellular processes dependent upon changes in gene expression. Histone deacetylases (HDACs) lead to the compaction of [...]

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The CXC-Chemokine CXCL4 Interacts with Integrins Implicated in Angiogenesis

Aidoudi S, Bujakowska K, Kieffer N, Bikfalvi A (2008) The CXC-Chemokine CXCL4 Interacts with Integrins Implicated in Angiogenesis. PLoS ONE 3(7): e2657. doi:10.1371/journal.pone.0002657

The human CXC-chemokine CXCL4 is a potent inhibitor of tumor-induced angiogenesis. Considering that CXCL4 is sequestered in platelet α-granules and released following platelet activation in the vicinity of vessel wall injury, we tested [...]

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Seule et Universelle Eglise des Fumeurs de Dieu

Ah ! le culte du tabac érigé en religion avec ses églises avec le zinc en guise d’autel et sa sainte trinité, la fumée, le feu et les cendres.
Voici une des rares utilités de la religion à mes yeux Oui, c’est jouer avec la loi pour se planquer derrière la liberté de religion, [...]

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NoToPope Coalition protests Pope and World Youth Day

[update] Quand même :
SYDNEY (Reuters) – Anti-protest laws imposed for Pope Benedict’s visit to Sydney this week, which could see protesters arrested for annoying Catholic pilgrims, were unconstitutional, a court ruled on Tuesday.
Ils pourront dire ce qu’ils pensent des conseils “pas de capote” tranquillement
[/update]

A Coalition has formed to peacefully protest Pope Benedict’s visit to [...]

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Variants of ST8SIA1 Are Associated with Risk of Developing Multiple Sclerosis

Variants of ST8SIA1 Are Associated with Risk of Developing Multiple Sclerosis:
by Seema Husain, Cagri Yildirim-Toruner, Justin P. Rubio, Judith Field, Marvin Schwalb, Stuart Cook, Marcella Devoto, Emilia Vitale

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system of unknown etiology with both genetic and environmental factors playing a role in susceptibility. To [...]

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Types Of Genes Necessary For Brain Development Discovered

Types Of Genes Necessary For Brain Development Discovered: “Researchers from Harvard Medical School and Brandeis University have successfully completed a full-genome RNAi screen in neurons, showing what types of genes are necessary for brain development.”

Sepp KJ, Hong P, Lizarraga SB, Liu JS, Mejia LA, et al. (2008) Identification of Neural Outgrowth Genes using Genome-Wide RNAi. [...]

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Altenberg 16, Richard Dawkins & …

En faisant un tour pour trouver de la lecture sur les “Altenberg 16″ qui nous préparent la prochaine révolution de la ToE (y a même le père Stuart Pivar qui en fait partie), je suis tombé sur une version française de la réponse que Richard Dawkins à fait au sujet de la bande des 16, [...]

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mad scientists in synthetic biology

io9 wants to encourage mad scientists in every field, but especially in the area of synthetic biology. That’s because synthetic biologists are the people who are going to build new life forms, like ligers and unicorns and people with claws and glowing eyes. OK, they might build bacteria that can clean up oil spills and [...]

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