Picks

The Longevity Pill?
Drugs much more powerful than the resveratrol found in red wine will be tested to treat diabetes.Well, red wine will be for the moment.

Science and Engineering Visualization Challenge

Dogs Can Classify Complex Photos In Categories Like Humans Do

Scientists, Teachers and Firefighters ‘Most Prestigious’ JobsGlad to know that I have a prestigious job, could I [...]

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Steve Fever

Steve Fever
Countless tiny machines hijack the living, borrowing their hands, eyes, and ears, as the machines strive to resurrect just one man.
By Greg Egan

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Free! BioScapes 2007 Competition Poster

And the winner is a Brainbow image!
Dr. Jean Livet
Dr. Jeff Lichtman Laboratory
Harvard University
Cambridge, MA, USA
Specimen: “Brainbow” Mouse Brain Stem
Technique: Confocal

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PLoS ONE Picks

Lévesque M, Gatien S, Finnson K, Desmeules S, Villiard É, et al. (2007) Transforming Growth Factor: β Signaling Is Essential for Limb Regeneration in Axolotls. PLoS ONE 2(11): e1227. doi:10.1371/journal.pone.0001227
Fox Keller E, Harel D (2007) Beyond the Gene. PLoS ONE 2(11): e1231. doi:10.1371/journal.pone.0001231
Weng W, Sukowati EW, Sheng G (2007) On Hemangioblasts in Chicken. PLoS ONE [...]

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Therapeutic angiogenesis of mouse hind limb ischemia by novel peptide activating GRP78 receptor on endothelial cells

Therapeutic angiogenesis of mouse hind limb ischemia by novel peptide activating GRP78 receptor on endothelial cells
Britta Hardy, Alexander Battler, Chana Weiss, Orly Kudasi, Annat Raiter
Biochem Pharmacol (2007), doi:10.1016/j.bcp.2007.10.008

Therapeutic angiogenesis emerged as a non-invasive mean of promoting neovascularization in ischemic tissues. We have searched for new molecules that induce angiogenesis by screening a phage display [...]

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Haemodynamics determined by a genetic programme

Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch
Kenta Yashiro, Hidetaka Shiratori & Hiroshi Hamada
Nature Vol 450 | 8 November 2007 | doi:10.1038/nature06254

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A Network Analysis of the Human T-Cell Activation Gene Network Identifies Jagged1 as a Therapeutic Target for Autoimmune Diseases

Palacios R, Goni J, Martinez-Forero I, Iranzo J, Sepulcre J (2007) A Network Analysis of the Human T-Cell Activation Gene Network Identifies Jagged1 as a Therapeutic Target for Autoimmune Diseases.
PLoS ONE 2(11): e1222. doi:10.1371/journal.pone.0001222

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Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
Junying Yu, Maxim A. Vodyanik, Kim Smuga-Otto, Jessica Antosiewicz-Bourget, Jennifer L. Frane, Shulan Tian, Jeff Nie, Gudrun A. Jonsdottir, Victor Ruotti, Ron Stewart, Igor I. Slukvin, James A. Thomson
www.sciencexpress.org 20 November 2007 Page 1 / doi: 10.1126/science.1151526

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Notch Regulates Wound Healing

Chigurupati S, Arumugam TV, Son TG, Lathia JD, Jameel S, et al (2007) Involvement of Notch Signaling in Wound Healing. PLoS ONE 2(11): e1167. doi:10.1371/journal.pone.0001167

The Notch signaling pathway is critically involved in cell fate decisions during development of many tissues and organs. In the present study we employed in vivo and cell culture models [...]

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Induction of Pluripotent Stem Cells from Adult Human Fibroblasts

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, and Shinya Yamanaka

Successful reprogramming of differentiated human somatic cells into a pluripotent state would allow creation of patient- and disease-specific stem cells. We previously reported generation of induced pluripotent stem (iPS) cells, [...]

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